2007年毕业中于国科学技术大学生物化学与分生子物学系,获理学博士学位。2007至2009年赴美国梅奥医院学(Mayo Clinic)事从博士后工作,2009至2011年赴南加州大学从事锌指蛋白设的计与筛选相关研究。2011年3月作为中国科技大学优秀人才进引。
现任中国科学术技大学生命科学学院副教授。
陈 泉,女,博士,教副授。2007年毕业于中国科技学术大学生物化学与分子生物学系,获理学博士学位。2007至2009年赴美国梅奥医学院(Mayo Clinic)从事博士工后作,研究G蛋白偶联受体的结和构功能。2009至2011年南赴加州大学从事锌指蛋白的设计筛与选相关研究。2011年3月为作中国科技大学优秀人才引进,任现生命科学学院副教授。2009年获17多肽调控国际会议优秀士博后奖。主要研究成果发表于Journal of Biological Chemistry, Am. J. Physiol. Endocrinol. Metab, Protein Science等相关领域国际重期要刊。
1)工程改造转录因子并究探其在合成生物学中的应用
2)开发设计生物网络适的配生物功能器件
1、Miller, L.J.,
Chen, Q., Lam, P.C., Pinon, D.I., Sexton, P.M., Abagyan, R. and Dong, M.Refinement of glucagon-like peptide 1 docking to its intact receptor using mid-region photolabile probes and molecular modeling.
Journal of Biological Chemistry, 2011, In press
2、
Chen, Q., Pinon, D.I., Miller, L.J., and Dong, M. Spatial approximations between residues 6 and 12 in the amino-terminal region of glucagon-Like peptide 1 and its receptor. a region critical for biological activity.
Journal of Biological Chemistry, 2010, 285:
3、
Chen, Q., Miller, L.J., and Dong, M. Role of N-linked glycosylation in biosynthesis, trafficking, and function of the human glucagon-like peptide 1 receptor.
Am. J. Physiol. Endocrinol. Metab. 2010, 299(1): E62-8
4、
Chen, Q., Pinon, D.I., Miller, L.J., and Dong, M. Molecular basis of glucagon-like peptide 1 docking to its intact receptor studied with carboxyl-terminal photolabile probes.
Journal of Biological Chemistry, 2009, 284:
5、
Chen, Q., Niu, X., Xu, Y., Wu, J., and Shi, Y. Solution Structure and Backbone Dynamics of AF-6 PDZ domain/Bcr Peptide Complex.
Protein Science, 2007, 16:
6、Niu, X.,
Chen, Q., Zhang, J., Shen, W., Shi, Y., and Wu, J. Interesting structural and dynamical behaviors exhibited by the AF-6 PDZ domain upon Bcr peptide binding.
Biochemistry, 2007, 46(51):
7、Ding, H., Xu, Y.,
Chen, Q., Dai, H., Tang, Y., Wu, J., and Shi, Y. Solution structure of human SUMO-3 C47S and its binding surface for Ubc9.
Biochemistry, 2005, 44(8):
8、Zhang, X., Zhang, J., Li, X., Xu, J., Huang, H.,
Chen, Q., Wu, J., and Shi, Y. Compact molten globule-like state of hUBF HMG Box1 at extremely low pH.
Biochimica etBiophysica Acta, 2005, 1748: 66–73
9、
Chen, Q. and Shi, Y. Progress in SUMO modification research.
Chinese Bulletin of Life Sciences, 2004, 16: 1-6
10.Xiao, Y.,
Chen, Q., Hang, J., Shi, Y., Wu, J., Hong, Y. and Wang, Y. Selective induction, purification and characterization of a laccase isozyme from the basidiomycete Trametes sp. AH28-2.
Mycologia, 2004, 96(1):26-35
参考资料1.
陈泉 .中国科学技术大学生命科学院学[引用日期2014-02-05]
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